NEW: Institut Esthederm’s Intensive NAD+ Innovation
Restoring Skin Quality from Within: Institut Esthederm’s Intensive NAD+ Innovation
Flawless bare skin, luminous and even skin is what we desire, et daily life conspires against it: fatigue, hormonal fluctuations, seasonal changes, and environmental stress leave their mark in redness, pigmentation, dullness, and uneven texture. Institut Esthederm, with forty years of research into cellular aging, has unveiled a new frontier in ecobiology — the Intensive NAD+ range — designed to restore skin quality from within by replenishing the skin’s own reserves of NAD+, a coenzyme essential to cellular vitality.
NAD+ (nicotinamide adenine dinucleotide) is a molecule at the heart of cellular life. It regulates energy production, DNA repair, antioxidant defenses, and inflammatory responses. With age and oxidative stress, NAD+ reserves decline, leaving skin vulnerable. Direct application is impossible — NAD+ molecules are too large to penetrate the skin barrier. The solution lies in niacinamide, a precursor that fuels NAD+ synthesis. Institut Esthederm’s innovation combines niacinamide with a plant-based NAD+ booster that stimulates the NAMPT enzyme, enhancing conversion and amplifying efficacy. This synergy reduces collagen-degrading enzymes like MMP-1, strengthens dermal components, and restores the skin’s ability to renew itself.
Clinical studies under dermatological supervision demonstrated significant improvements across all parameters of skin quality. Radiance increased by more than a third, redness was reduced by nearly three quarters, and complexion uniformity improved dramatically. Texture was refined, pores tightened, and dark spots diminished. After two months of use, every woman in the study reported feeling confident without makeup.
The Intensive NAD+ Serum, with 10% niacinamide and a NAD+ booster, is a lightweight emulsion that targets redness, uneven tone, and pore visibility. Visible efficacy is achieved after just one month. The Intensive NAD+ Cream, with 5% niacinamide and the same booster, is a delicate dew cream that smooths, brightens, and refines texture. Clinical studies showed an 82% improvement in overall skin quality after two months.
Dr. Elodie Valin, PhD, Scientific Valorization Director at NAOS, explains: “The NAD+ booster stimulates NAMPT, promoting niacinamide’s conversion into NAD+. This mechanism is fundamental for the proper functioning of skin processes essential for quality. Together, they restore reserves depleted by age and stress, ensuring resilience and radiance.”
NAD+ is dominating headlines because it represents a new philosophy in beauty: deep restoration rather than surface correction. By replenishing cellular reserves, Institut Esthederm’s Intensive NAD+ range offers a scientifically grounded path to radiance, proving that true skin quality begins within.

